Techniques in this family
Depth Filtration
$30k-$300k
Cell debris removal, polish clarification
Diafiltration
$80k-$500k
Buffer exchange, salt removal
Microfiltration
$100k-$700k
Cell removal, clarification
Nanofiltration
$150k-$800k
Salt/sugar separation, desalting
Ultrafiltration
$100k-$600k
Protein concentration & buffer exchange
Molecule families typically separated
Other separation families
Frequently Asked Questions
When does this category beat other separation approaches?
Pick this family when the dominant property gap between your target and impurities matches its separation mechanism. See the individual technique pages for parameter ranges.
Can these techniques be combined in one process?
Yes — most commercial processes use 2-3 techniques from different families in series. Use the route generator in untangle.bio to explore combinations.
What CAPEX should I budget?
Capital costs span 1-2 orders of magnitude depending on scale and GMP requirements. See each technique page for ranges, or use the CAPEX estimator under /tools.
Build a process around these techniques
Drag any of these unit operations into a flowsheet and simulate mass balance with real-world cost data.
Open untangle.bio