Phase-Change Separation

Separation by inducing a phase boundary: crystallization (solid from solution), evaporation and spray drying (vapor from liquid), precipitation (solubility shift). Bulk recovery economics.

Frequently Asked Questions

When does this category beat other separation approaches?

Pick this family when the dominant property gap between your target and impurities matches its separation mechanism. See the individual technique pages for parameter ranges.

Can these techniques be combined in one process?

Yes — most commercial processes use 2-3 techniques from different families in series. Use the route generator in untangle.bio to explore combinations.

What CAPEX should I budget?

Capital costs span 1-2 orders of magnitude depending on scale and GMP requirements. See each technique page for ranges, or use the CAPEX estimator under /tools.

Build a process around these techniques

Drag any of these unit operations into a flowsheet and simulate mass balance with real-world cost data.

Open untangle.bio